Collaborative Cryo-FIB research
Abstract submitted to Microscopy Society of America 2006 Meeting
Collaborative SEM study on Mouse Retina and RPE
I am working with Dr. Dennis Defoe at Eastern Tennessee State University to characterize Retinal Pigmented Epitheliial(RPE) changes in “knock out” vs normal mice. A negative cell cycle regulatory protein gene, Kip1 has been deleted leading to excell cell proliferation. Microvillous processes appear to be altered. We are currently investigating the changes that occur.